The Detroit Lions and the Carolina Panthers set to clash in Week 4

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By Olivia Martinez • Updated Oct 5, 2026 at 04:30

5 things to watch: Lions at Panthers - Detroit Lions — The Detroit Lions and the Carolina Panthers set to clash in Week 4

The Detroit Lions will face the Carolina Panthers in Week 4 on Sunday Night Football. The Panthers seek to enhance their run game against the Lions, while the Lions have revised their depth chart. Fans and analysts are watching key aspects of the matchup, including betting tips and predictions. The Panthers aim to launch their run game going against the Lions, while the Lions have updated their depth chart for the game.

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